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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPP4R4 All Species: 14.24
Human Site: S814 Identified Species: 31.33
UniProt: Q6NUP7 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6NUP7 NP_066009.2 873 99452 S814 L G K T S V L S L A D D S F R
Chimpanzee Pan troglodytes XP_522937 1109 124026 S1050 L G K T S V L S L T D D S F R
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_547959 916 103055 G849 A S K S S T A G Y T S S V S G
Cat Felis silvestris
Mouse Mus musculus Q8C0Y0 875 99462 S816 L V R T A M L S L T D D S F R
Rat Rattus norvegicus NP_001128104 821 93759 A760 V S K S S T L A H S S S V S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511225 842 94937 Q782 H V D K C V N Q G F S T G Y P
Chicken Gallus gallus XP_421339 873 99507 S814 M G K G C M L S F S D D S F R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_696336 875 98944 D809 S P M L P L N D D N L R P H H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393531 722 82259 G664 E E E K K I S G M A I G K A P
Nematode Worm Caenorhab. elegans NP_495884 986 111167 S915 T S P L S S S S L P S S G Y G
Sea Urchin Strong. purpuratus XP_781974 792 88319 S734 P A S A P S I S S R K A A S K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.1 N.A. 88.3 N.A. 90.7 83.8 N.A. 65.2 79.8 N.A. 59.2 N.A. N.A. 31.2 23.2 40.8
Protein Similarity: 100 78 N.A. 90.5 N.A. 95 88.5 N.A. 78.4 91.1 N.A. 77.1 N.A. N.A. 49.8 45.5 60.9
P-Site Identity: 100 93.3 N.A. 13.3 N.A. 66.6 20 N.A. 6.6 60 N.A. 0 N.A. N.A. 6.6 20 6.6
P-Site Similarity: 100 93.3 N.A. 20 N.A. 86.6 46.6 N.A. 13.3 80 N.A. 6.6 N.A. N.A. 26.6 26.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 10 10 0 10 10 0 19 0 10 10 10 0 % A
% Cys: 0 0 0 0 19 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 10 10 0 37 37 0 0 0 % D
% Glu: 10 10 10 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 10 10 0 0 0 37 0 % F
% Gly: 0 28 0 10 0 0 0 19 10 0 0 10 19 0 28 % G
% His: 10 0 0 0 0 0 0 0 10 0 0 0 0 10 10 % H
% Ile: 0 0 0 0 0 10 10 0 0 0 10 0 0 0 0 % I
% Lys: 0 0 46 19 10 0 0 0 0 0 10 0 10 0 10 % K
% Leu: 28 0 0 19 0 10 46 0 37 0 10 0 0 0 0 % L
% Met: 10 0 10 0 0 19 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 19 0 0 10 0 0 0 0 0 % N
% Pro: 10 10 10 0 19 0 0 0 0 10 0 0 10 0 19 % P
% Gln: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % Q
% Arg: 0 0 10 0 0 0 0 0 0 10 0 10 0 0 37 % R
% Ser: 10 28 10 19 46 19 19 55 10 19 37 28 37 28 0 % S
% Thr: 10 0 0 28 0 19 0 0 0 28 0 10 0 0 0 % T
% Val: 10 19 0 0 0 28 0 0 0 0 0 0 19 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 0 0 0 0 19 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _